Trifluoroacetic acid (TFA) is an organofluorine compound with the chemical formula CF3CO2H. It is a structural analogue of acetic acid with all three of the acetyl group's hydrogen atoms replaced by fluorine atoms and is a colorless liquid with a vinegar-like odor.
Trifluoroacetic acid is a corrosive acid but it does not pose the hazards associated with hydrofluoric acid because the carbon-fluorine bond is not labile. Only if heated or treated with ultrasonic waves will it decompose into hydrofluoric acid. TFA is harmful when inhaled, causes severe skin burns and is toxic for aquatic organisms even at low concentrations.
Trifluoroacetic acid appears as a colorless fuming liquid with a pungent odor. Soluble in water and denser than water.
Trifluoroacetic acid (TFA) is an extremely corrosive acid which causes severe damage when in contact with skin, eyes, and tissue of mucous membrane.
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