BOC Sciences is committed to providing customers with high-quality and stable isotope nitrogen-15 labeled peptides, amino acids, nucleic acids, steroids, APIs, impurities, inhibitors, metabolites, carbohydrates, polymers, fatty acids and lipids, as well as other products.

Nitrogen-15

Nitrogen is an important life element that affects the metabolism of organisms and is widely distributed in nature. There are two natural isotopes of nitrogen, nitrogen-14 (¹⁴N) and nitrogen-15 (¹⁵N). Nitrogen-14 is the most common nitrogen isotope (non-radioactive) and makes up 99% of natural nitrogen. Nitrogen-15 is a rare nitrogen stable isotope (non-radioactive). In addition, because all radioisotopes of nitrogen have short half-lives, the longest-lived nitrogen-13 has a half-life of only a few minutes. Thus, there is no suitable radioisotope for nitrogen as a tracer atom. The stable isotope nitrogen-15 has stable performance, and its content can be accurately detected by mass spectrometry and emission spectroscopy. Therefore, nitrogen-15 can be used as a tracer atom of nitrogen compounds and has been widely used in many fields such as agriculture, biomedicine, environmental science, etc.

Nitrogen-15 labeled compounds

Nitrogen-15 labeled compound refers to using the stable isotope nitrogen-15 instead of the original nitrogen in the compound. Nitrogen-15 is the only applicable tracer in biomedical experiments. Nitrogen-15 labeled amino acids, peptides, carbohydrates, nucleic acids, lipids, steroids, and other compounds are widely used in medicine, life sciences, environmental sciences, agricultural research and other fields.

• Medicine: Nitrogen-15 labeled compounds can be used for studies on metabolic transformation, exploration of metabolic reaction mechanisms, auxiliary clinical diagnosis, monitoring of lesions, clinical nutrition research, etc.
• Life sciences: Nitrogen-15 labeled compounds can be used in the biosynthesis of natural organic matter, pharmacokinetics research, drug metabolite identification, pharmacological research, etc.
• Environmental science: Nitrogen-15 is a good pollutant indicator. Nitrogen-15 labeled compounds can be used in various researches such as air and water quality.
• Agricultural research: Nitrogen-15 labeled compounds can be used in plant physiology and biochemistry research, soil and plant nutrition research, plant protection research, crop improvement, biological nitrogen fixation, etc.

Source: https://isotope.bocsci.com/isotopic-labels/nitrogen-15-3848.html